Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11800230 | 0.87 | TSHR (0.64) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL27741870 | 0.84 | FAAH (0.54) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| Acetic Acid SCHEMBL28974131 | 0.84 | TSHR (0.60) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL23260954 | 0.82 | TSHR (0.62) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL31384037 | 0.81 | FAAH (0.52) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL31657295 | 0.80 | ADRB2 (0.57) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL29743339 | 0.80 | FAAH (0.51) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL12412855 | 0.80 | TSHR (0.73) | FAAHSMN1; SMN2MAPK1KMT2AADRB2 | |
| SCHEMBL7778553 | 0.79 | FAAH (0.50) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL9139288 | 0.79 | FAAH (0.50) | FAAHSMN1; SMN2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030814-A1 | METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES | DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) | 2020-02-13 | — | — | WO | disclosed |