SCHEMBL21706804

SCHEMBL21706804

COC1OC(CO)C(O)C(OCc2ccccc2)C1OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 3/20 0.60
SLC6A2 P23975 1/20 0.58
SSTR1 P30872 1/20 0.52
SSTR2 P30874 1/20 0.52
SSTR4 P31391 1/20 0.52
SSTR3 P32745 1/20 0.52
SSTR5 P35346 1/20 0.52
LGALS3 P17931 5/20 0.51
BCHE P06276 1/20 0.49
OGA O60502 1/20 0.47
LGALS9 O00182 2/20 0.46
LGALS4 P56470 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7152294 1.00 LGALS8 (0.60) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL7152720 1.00 LGALS8 (0.60) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL3156075 1.00 LGALS8 (0.60) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL3152068 0.96 LGALS8 (0.58) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL7150592 0.96 LGALS8 (0.58) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL13380951 0.93 LGALS8 (0.53) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL6947007 0.93 LGALS8 (0.53) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL25084120 0.92 LGALS8 (0.66) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL20671054 0.92 LGALS8 (0.66) LGALS8SLC6A2SSTR1SSTR2SSTR4
SCHEMBL20658674 0.92 LGALS8 (0.66) LGALS8SLC6A2SSTR1SSTR2SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020033971-A1 USE OF IGF-2 RECEPTOR AGONIST LIGANDS FOR TREATMENT OF ANGELMAN SYNDROME AND AUTISM NEW YORK UNIVERSITY (US) 2020-02-13 WO disclosed
WO-2020033972-A1 USE OF MANNOSE 6 PHOSPHATE AND MODIFICATIONS THEREOF FOR MEMORY ENHANCEMENT AND REDUCING MEMORY IMPAIRMENT NEW YORK UNIVERSITY (US) 2020-02-13 WO disclosed