Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 3/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC5A2 | P31639 | 5/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.51 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.47 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.47 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.47 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.47 |
| ▸ | LGALS3 | P17931 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13380951 | 1.00 | LGALS8 (0.53) | LGALS8SLC6A2SLC5A2SLC5A1SSTR5 | |
| SCHEMBL7152720 | 0.93 | LGALS8 (0.60) | LGALS8SLC6A2SSTR5SSTR1SSTR2 | |
| SCHEMBL21706804 | 0.93 | LGALS8 (0.60) | LGALS8SLC6A2SSTR5SSTR1SSTR2 | |
| SCHEMBL7152294 | 0.93 | LGALS8 (0.60) | LGALS8SLC6A2SSTR5SSTR1SSTR2 | |
| SCHEMBL3156075 | 0.93 | LGALS8 (0.60) | LGALS8SLC6A2SSTR5SSTR1SSTR2 | |
| SCHEMBL6951099 | 0.90 | SSTR5 (0.54) | LGALS8SSTR5SSTR1SSTR2SSTR4 | |
| SCHEMBL7150592 | 0.89 | LGALS8 (0.58) | LGALS8SLC6A2SLC5A2SSTR5SSTR1 | |
| SCHEMBL3152068 | 0.89 | LGALS8 (0.58) | LGALS8SLC6A2SSTR5SSTR1SSTR2 | |
| SCHEMBL3660543 | 0.88 | SLC6A2 (0.48) | LGALS8SLC6A2SLC5A2SLC5A1SSTR5 | |
| SCHEMBL15481400 | 0.86 | SLC6A2 (0.57) | LGALS8SLC6A2SLC5A2SLC5A1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534481-B1 | Antithrombin III binding domain consisting of a concatenation of five monosaccharides supporting a total of two carboxylic acid functions and at least four sulpho groups, said domain being directly bound at the non-reducing end by a thrombin | SANOFI-SYNTHELABO (FR) | 2003-03-18 | — | — | US | disclosed |
| US-6528497-B1 | Anticoagulant and antithrombotic like heparin; hexadeca saccharides of three distinct sequences: a sulphated penta saccharide sequence DEFGH, a non-sulphated heptasaccharide sequence Z(MN)3 and a sulphated tetrasaccharide sequence VWXY. | SANOFI-SYNTHELABO (FR) | 2003-03-04 | — | — | US | disclosed |
| EP-0912613-B1 | SYNTHETIC POLYSACCHARIDES, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |