Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527425 | 0.95 | PKM (0.40) | PKMHTTMEN1KMT2ACYP1A2 | |
| SCHEMBL14473403 | 0.87 | MGAM (0.41) | MEN1KMT2ACYP2C9TP53ALDH1A1 | |
| SCHEMBL12590379 | 0.87 | MGAM (0.41) | MEN1KMT2ACYP2C9TP53ALDH1A1 | |
| SCHEMBL10793775 | 0.86 | ALDH1A1 (0.50) | PKMHTTMEN1KMT2ACYP1A2 | |
| SCHEMBL9261661 | 0.86 | CYP1A2 (0.52) | CYP1A2ALDH1A1USP2ALOX15TDP1 | |
| SCHEMBL10793779 | 0.86 | ALDH1A1 (0.50) | PKMHTTMEN1KMT2ACYP1A2 | |
| SCHEMBL2721040 | 0.85 | — | — | |
| SCHEMBL19853824 | 0.84 | EPHX2 (0.39) | PKMHTTMEN1KMT2ACYP1A2 | |
| SCHEMBL9289506 | 0.83 | TLR4 (0.40) | MEN1KMT2ACYP2C9TP53ALDH1A1 | |
| SCHEMBL7790319 | 0.82 | MGAM (0.40) | MEN1KMT2AALDH1A1USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020030814-A1 | METHODS FOR DELAYING OCCURRENCE OF NEW-ONSET TYPE 2 DIABETES AND FOR SLOWING PROGRESSION OF AND TREATING TYPE 2 DIABETES | DALCOR PHARMA UK LTD., LEATHERHEAD, ZUG BRANCH (CH) | 2020-02-13 | — | — | WO | disclosed |