SCHEMBL21707343

SCHEMBL21707343

c1ccc(-c2nc(-c3ccc(-c4ncc5ccccc5n4)cc3)nc(-c3ccc4sc5ccccc5c4c3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
RECQL P46063 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ATM Q13315 1/20 0.41
MAOA P21397 4/20 0.37
MAOB P27338 4/20 0.37
PDE5A O76074 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GPR3 P46089 1/20 0.36
ABCG2 Q9UNQ0 3/20 0.36
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19165889 0.94 CYP1A2 (0.43) CYP1A2NPC1LMNAMAPTRECQL
SCHEMBL19165843 0.89 CYP1A2 (0.41) CYP1A2NPC1LMNAMAPTRECQL
SCHEMBL19165132 0.89 CYP1A2 (0.41) CYP1A2NPC1LMNAMAPTRECQL
SCHEMBL19165172 0.89 CYP1A2 (0.41) CYP1A2NPC1LMNAMAPTRECQL
SCHEMBL23686640 0.85 GPR3 (0.48) CYP1A2LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL15501884 0.85 GPR3 (0.48) CYP1A2LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL25645941 0.84 GPR3 (0.47) CYP1A2LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL18378311 0.83 LIMK1 (0.45) CYP1A2NPC1LMNAMAPTRECQL
SCHEMBL18212422 0.82 GPR3 (0.45) CYP1A2LMNAMAPTRAB9ASMN1; SMN2
SCHEMBL25463418 0.82 MAPT (0.43) CYP1A2NPC1LMNAMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032428-A1 ORGANIC ELECTRIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRIC ELEMENT AND ELECTRONIC DEVICE USING SAME 덕산네오룩스 주식회사 2020-02-13 WO disclosed