Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 10/20 | 0.60 |
| ▸ | CA1 | P00915 | 10/20 | 0.60 |
| ▸ | CA2 | P00918 | 10/20 | 0.60 |
| ▸ | CA9 | Q16790 | 10/20 | 0.60 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708021 | 0.91 | MAPT (0.68) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL5041112 | 0.88 | EGFR (0.73) | KDM1ACYP1A2CYP2C19CA12CA1 | |
| SCHEMBL10464406 | 0.88 | MAPT (0.65) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL4789312 | 0.88 | SMN1; SMN2 (0.69) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL790315 | 0.87 | MAPT (0.64) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL21708010 | 0.87 | GAA (0.64) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL525606 | 0.87 | MAOA (0.64) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL3045328 | 0.85 | CA12 (0.55) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL20530863 | 0.85 | SMN1; SMN2 (0.72) | CYP1A2CYP2C19CA12CA1CA2 | |
| SCHEMBL3044989 | 0.85 | L3MBTL1 (0.60) | KDM1ACYP1A2CYP2C19EGFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | UNIVERSITY OF HEIDELBERG (DE) | 2020-02-27 | — | — | US | disclosed |
| EP-3611256-A1 | APPLICATION OF IMIDAZOPYRIDINE DERIVATIVES IN REGENERATIVE MEDICINE | Universität Heidelberg (DE) | 2020-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062719-A1 | Application of Imidazopyridine Derivatives in Regenerative Medicine | DOT1L, NSD1, KDM3A | KDM1A 18/4885CYP1A2 3477/4885CYP2C19 3845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.