Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 15/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 3/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | BAD | Q92934 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356095 | 0.80 | ACHE (0.49) | MAPK1 | |
| SCHEMBL461129 | 0.80 | ACHE (0.49) | MAPK1 | |
| SCHEMBL11701599 | 0.68 | ACHE (0.39) | MAPK1MAOB | |
| SCHEMBL77567 | 0.68 | TSHR (0.69) | MCL1CYP1A2POLBCYP2D6TSHR | |
| SCHEMBL11450837 | 0.65 | ACHE (0.46) | MAPK1 | |
| SCHEMBL6733945 | 0.65 | ACHE (0.49) | MAPK1 | |
| SCHEMBL29435143 | 0.65 | ACHE (0.49) | MAPK1 | |
| SCHEMBL119641 | 0.65 | ACHE (0.49) | MAPK1 | |
| SCHEMBL7526468 | 0.65 | ACHE (0.46) | MAPK1 | |
| SCHEMBL11451394 | 0.64 | ALDH1A1 (0.44) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2347655-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS | Syngenta Participations AG. (CH) | 2011-07-27 | — | — | EP | claimed |