Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | BCL9 | O00512 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985790 | 0.90 | BCL9 (0.55) | HDAC3HDAC1HDAC2POLBKMT2A | |
| SCHEMBL28714786 | 0.90 | KMT2A (0.51) | HDAC3HDAC1HDAC2POLBKMT2A | |
| SCHEMBL5822065 | 0.86 | KMT2A (0.61) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL5701834 | 0.85 | BCL9 (0.50) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL1999397 | 0.84 | KIF11 (0.49) | KMT2ASMN1; SMN2LMNAALDH1A1MAPT | |
| SCHEMBL9195803 | 0.83 | HDAC3 (0.44) | HDAC3HDAC1HDAC2POLBKMT2A | |
| SCHEMBL9195807 | 0.83 | HDAC3 (0.44) | HDAC3HDAC1HDAC2POLBKMT2A | |
| SCHEMBL27946993 | 0.83 | KMT2A (0.58) | HDAC3HDAC1HDAC2POLBKMT2A | |
| SCHEMBL9195858 | 0.82 | HDAC3 (0.43) | HDAC3HDAC1HDAC2POLBKMT2A | |
| SCHEMBL9195849 | 0.82 | HDAC3 (0.43) | HDAC3HDAC1HDAC2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |