SCHEMBL1999397

SCHEMBL1999397

CCCCC(=O)Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.49
KMT2A Q03164 6/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 2/20 0.47
HTT P42858 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 1/20 0.47
HSD17B10 Q99714 1/20 0.47
BCL9 O00512 1/20 0.45
CTNNB1 P35222 1/20 0.45
ALOX5 P09917 3/20 0.45
PSEN1 P49768 3/20 0.45
MEN1 O00255 2/20 0.44
KDM4E B2RXH2 1/20 0.44
RECQL P46063 1/20 0.44
PTGES O14684 2/20 0.44
PPARG P37231 2/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
MAOB P27338 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31346764 0.94 KMT2A (0.56) KIF11KMT2ASMN1; SMN2LMNAHTT
SCHEMBL1045008 0.90 BCL9 (0.55) KIF11KMT2ASMN1; SMN2LMNAHTT
SCHEMBL1860685 0.89 ALOX5 (0.47) KMT2AALOX5PSEN1MEN1PTGES
SCHEMBL5822065 0.86 KMT2A (0.61) KMT2ASMN1; SMN2LMNAHTTALDH1A1
SCHEMBL28588550 0.85 KMT2A (0.49) KMT2ASMN1; SMN2LMNAHTTALDH1A1
SCHEMBL21708560 0.84 HDAC3 (0.52) KMT2ASMN1; SMN2LMNAHTTALDH1A1
SCHEMBL1998642 0.84 KMT2A (0.41) KMT2ASMN1; SMN2MAPTALOX5PSEN1
SCHEMBL9188927 0.83 LSS (0.47) KIF11KMT2ASMN1; SMN2LMNAHTT
SCHEMBL9188919 0.83 LSS (0.47) KIF11KMT2ASMN1; SMN2LMNAHTT
SCHEMBL1294868 0.83 KMT2A (0.58) KIF11KMT2ASMN1; SMN2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-3609870-A1 SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF Bayer Aktiengesellschaft (DE) 2020-02-19 EP disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed