Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PTGFR | P43088 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708482 | 0.90 | CES2 (0.33) | FFAR1FFAR4KMT2AMAPT | |
| SCHEMBL21708569 | 0.89 | KMT2A (0.33) | FFAR1FFAR4KMT2ASLC6A3PTGFR | |
| SCHEMBL21708548 | 0.85 | MEN1 (0.35) | KMT2ASLC6A3SMN1; SMN2MAPT | |
| SCHEMBL21708737 | 0.83 | CES2 (0.33) | — | |
| SCHEMBL21708517 | 0.81 | PTGFR (0.35) | FFAR1FFAR4SLC6A3PTGFRSMN1; SMN2 | |
| SCHEMBL21632072 | 0.81 | FFAR1 (0.44) | FFAR1FFAR4KMT2APTGFR | |
| SCHEMBL21656308 | 0.81 | FFAR1 (0.36) | FFAR1FFAR4KMT2A | |
| SCHEMBL21708707 | 0.81 | CCR1 (0.36) | KMT2A | |
| SCHEMBL21708544 | 0.80 | POLB (0.38) | KMT2A | |
| SCHEMBL21708512 | 0.80 | CCR1 (0.36) | KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |