Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 3/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 6/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708466 | 0.90 | F2R (0.36) | KCNK3KCNK9F2RPTGFRPDE2A | |
| SCHEMBL21708731 | 0.89 | POLB (0.41) | L3MBTL1POLBHTTNPSR1ALDH1A1 | |
| SCHEMBL21709050 | 0.88 | KMT2A (0.36) | HCRTR1GAAL3MBTL1HTTPPARG | |
| SCHEMBL21708746 | 0.84 | CNR2 (0.34) | KCNK3KCNK9POLBPPARG | |
| SCHEMBL21708631 | 0.83 | KMT2A (0.38) | GAAPOLBNPSR1ALDH1A1 | |
| SCHEMBL21708675 | 0.82 | CCR1 (0.37) | GAAHTTNPSR1ALDH1A1 | |
| SCHEMBL21708713 | 0.81 | KCNK3 (0.37) | KCNK3KCNK9F2RPTGFRPDE2A | |
| SCHEMBL21656299 | 0.81 | KCNK3 (0.37) | KCNK3KCNK9GAARXRARXRB | |
| SCHEMBL21708544 | 0.79 | POLB (0.38) | L3MBTL1POLBHTTNPSR1PPARG | |
| SCHEMBL21632117 | 0.79 | FFAR1 (0.41) | KCNK3KCNK9PTGFRGAARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |