Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 3/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708650 | 0.90 | KCNK3 (0.36) | F2RKCNK3KCNK9PTGFRVNN1 | |
| SCHEMBL21708544 | 0.89 | POLB (0.38) | PPARG | |
| SCHEMBL21708654 | 0.87 | MEN1 (0.38) | KCNK3PTGFRPPARGGAA | |
| SCHEMBL21708473 | 0.85 | CNR2 (0.34) | F2RKCNK3KCNK9PPARG | |
| SCHEMBL21708707 | 0.83 | CCR1 (0.36) | — | |
| SCHEMBL21708548 | 0.83 | MEN1 (0.35) | GAA | |
| SCHEMBL21656351 | 0.82 | APP (0.44) | KCNK3KCNK9FFAR1PTGFRAPP | |
| SCHEMBL21708512 | 0.82 | CCR1 (0.36) | GAA | |
| SCHEMBL21708582 | 0.82 | PTGFR (0.38) | F2RKCNK3KCNK9PTGFRAPP | |
| SCHEMBL21631974 | 0.81 | FFAR1 (0.45) | KCNK3KCNK9FFAR1PTGFRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| EP-3609870-A1 | SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |