Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21708731 | 0.92 | POLB (0.41) | KMT2AMEN1L3MBTL1PPARGTSHR | |
| SCHEMBL21708650 | 0.88 | KCNK3 (0.36) | L3MBTL1HCRTR1PPARGHTTGAA | |
| SCHEMBL21708631 | 0.86 | KMT2A (0.38) | KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL21708675 | 0.85 | CCR1 (0.37) | KMT2AMEN1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL21708746 | 0.83 | CNR2 (0.34) | KMT2AKDM4ECYP1A2CYP2C9PPARG | |
| SCHEMBL21708544 | 0.81 | POLB (0.38) | KMT2AMEN1L3MBTL1PPARGTSHR | |
| SCHEMBL21708711 | 0.81 | KMT2A (0.39) | KMT2AKDM4EL3MBTL1HTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL21708730 | 0.79 | CTDSP1 (0.36) | KMT2AMEN1KDM4ECTDSP1L3MBTL1 | |
| SCHEMBL21631933 | 0.79 | L3MBTL1 (0.51) | KMT2AMEN1KDM4ECTDSP1CYP1A2 | |
| SCHEMBL21656178 | 0.78 | L3MBTL1 (0.39) | KMT2AMEN1KDM4ECTDSP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |