Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | KRAS | P01116 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3755885 | 0.87 | MAPK1 (0.56) | KMT2AMAPK1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL1994318 | 0.85 | KMT2A (0.49) | KMT2AMAPK1SLC2A1SLC2A4KDM4E | |
| SCHEMBL2875254 | 0.83 | MAPK1 (0.62) | KMT2AMAPK1NPC1KDM4EALDH1A1 | |
| SCHEMBL7116065 | 0.83 | ALDH1A1 (0.46) | KMT2AMAPK1SLC2A1SLC2A4NPC1 | |
| SCHEMBL2398457 | 0.81 | KMT2A (0.52) | KMT2ASLC2A1SLC2A4NPC1SMN1; SMN2 | |
| SCHEMBL6026883 | 0.80 | KMT2A (0.51) | KMT2ASLC2A1SLC2A4NPC1SMN1; SMN2 | |
| SCHEMBL6199258 | 0.80 | MAPT (0.53) | KMT2AMAPK1NPC1KDM4EALDH1A1 | |
| SCHEMBL3327023 | 0.79 | MAPK1 (0.58) | KMT2AMAPK1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL28782497 | 0.79 | MAPK1 (0.49) | KMT2AMAPK1NPC1SMN1; SMN2KDM4E | |
| SCHEMBL5743633 | 0.79 | TUBB4A (0.45) | KMT2AMAPK1RAB9AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609869-A1 | SUBSTITUTED N-ARYLETHYL-2-ARYLQUINOLINE-4-CARBOXAMIDES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2020-02-19 | — | — | EP | disclosed |
| CN-110730776-A | Substituted N-arylethyl-2-arylquinoline-4-carboxamides and their use | 拜耳股份公司 | 2020-01-24 | — | — | CN | disclosed |