SCHEMBL21708925

SCHEMBL21708925

C#CCNCCc1cc(C)c2c(c1)OC(C)(C)O2

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21708850 0.79 ALOX15 (0.42) ACHETSHR
SCHEMBL21709188 0.76 CNR2 (0.39) TSHR
SCHEMBL21709146 0.69 TSHR (0.36) TSHR
SCHEMBL16330241 0.69 TSHR (0.48) TSHR
SCHEMBL21708900 0.63 CA12 (0.35)
SCHEMBL15984236 0.63 TSHR (0.50) TSHR
SCHEMBL21709158 0.63 ACHE (0.36) ACHETSHR
SCHEMBL30614477 0.63 POLB (0.56)
SCHEMBL14337784 0.62 TSHR (0.44) TSHR
SCHEMBL14337775 0.62 TSHR (0.44) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed