⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024452 | 0.82 | MMP1 (0.53) | — | |
| SCHEMBL16196732 | 0.82 | MMP1 (0.53) | — | |
| SCHEMBL5166336 | 0.80 | — | — | |
| SCHEMBL1039374 | 0.80 | — | — | |
| SCHEMBL28045868 | 0.80 | — | — | |
| SCHEMBL7524679 | 0.78 | MMP1 (0.50) | — | |
| Water SCHEMBL14563848 | 0.78 | MMP1 (0.50) | — | |
| SCHEMBL28778171 | 0.78 | MMP1 (0.54) | — | |
| SCHEMBL6990198 | 0.78 | — | — | |
| SCHEMBL1884481 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013135235-A1 | PROCESS FOR PRODUCING AND USING A GEL SYSTEM FOR OILFIELD AND GASFIELD APPLICATIONS, SUCH AS FRACKING AND WELL CLEANING, AND GEL SYSTEM PRODUCED BY THIS PROCESS | AME Trade & Development GmbH (DE) | 2013-09-19 | — | — | WO | claimed |
| EP-0146642-B1 | PROCESS FOR THE PREPARATION OF 4-AMINO-6,7-DIMETHOXY-2-(4-(FUROYL-2)-PIPERAZIN-1-YL)-QUINAZOLINE AND ITS PHYSIOLOGICALLY ACCEPTABLE SALT | LUDWIG HEUMANN & CO GMBH (DE) | 1988-01-20 | — | — | EP | claimed |
| EP-0146642-A1 | Process for the preparation of 4-amino-6,7-dimethoxy-2-(4-(furoyl-2)-piperazin-1-yl)-quinazoline and its physiologically acceptable salt | LUDWIG HEUMANN & CO GMBH (DE) | 1985-07-03 | — | — | EP | claimed |
| CN-118440039-A | Synthesis method of carbofuran marked by stable isotope | 上海化工研究院有限公司 | 2024-08-06 | — | — | CN | disclosed |
| EP-2346827-B1 | PYRIDINE DERIVATIVES AS VEGFR-2 RECEPTOR AND PROTEIN TYROSINE KINASE INHIBITORS | LEO PHARMA AS (DK) | 2013-11-13 | — | — | EP | disclosed |
| US-8350026-B2 | VEGF-2 receptor and protein tyrosine kinase inhibitors and pharmaceutical use thereof | LEO PHARMA A/S (DK) | 2013-01-08 | — | — | US | disclosed |
| US-20110190282-A1 | NOVEL VEGF-2 RECEPTOR AND PROTEIN TYROSINE KINASE INHIBITORS AND PHARMACEUTICAL USE THEREOF | LEO PHARMA A/S (DK) | 2011-08-04 | — | — | US | disclosed |
| EP-2346827-A1 | PYRIDINE DERIVATIVES AS VEGFR-2 RECEPTOR AND PROTEIN TYROSINE KINASE INHIBITORS | LEO PHARMA A/S (DK) | 2011-07-27 | — | — | EP | disclosed |
| EP-1765816-B1 | SUBSTITUTED 1-PROPIOLYLPIPERAZINES HAVING AN AFFINITY FOR THE MGLUR5 RECEPTOR IN ORDER TO TREAT PAINFUL CONDITIONS | GRUENENTHAL GMBH (DE) | 2010-03-10 | — | — | EP | disclosed |
| WO-2010022725-A1 | PYRIDINE DERIVATIVES AS VEGFR-2 RECEPTOR AND PROTEIN TYROSINE KINASE INHIBITORS | LEO PHARMA A/S (DK) | 2010-03-04 | — | — | WO | disclosed |
| EP-1551830-B1 | HETEROCYCLICALLY SUBSTITUTED INDOLINONES AND THEIR USE AS RECEPTOR TYROSINE KINASE INHIBATORS | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-04-08 | — | — | EP | disclosed |
| EP-0013361-A2 | Substituted N-halogenomethyl anilides, process for their preparation and use | BASF Aktiengesellschaft (DE) | 1980-07-23 | — | — | EP | disclosed |
| EP-0013360-A2 | N-substituted carboxylic acid anilides, process for their preparation as well as their use as fungicides | BASF Aktiengesellschaft (DE) | 1980-07-23 | — | — | EP | disclosed |
| EP-0012428-A1 | Substituted cyanamides, process for their preparation and their use as fungicides | BASF Aktiengesellschaft (DE) | 1980-06-25 | — | — | EP | disclosed |
| EP-0011282-A1 | Thienylbenzoic-acid derivatives, process for their production, and pharmaceutical preparations containing these compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |
| EP-0010673-A2 | Substituted N-propargyl anilines, process for their preparation and their use as fungicides | BAYER AG (DE) | 1980-05-14 | — | — | EP | disclosed |
| EP-0007643-A1 | Oxadiazolotriazine derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-02-06 | — | — | EP | disclosed |
| EP-0004332-A1 | Isoquinolines, process for their preparation, and pharmaceutical preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-10-03 | — | — | EP | disclosed |
| US-4148895-A | HYPOTENSIVE, ANTIARRHYMIA AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |
| US-4100165-A | Imidazo [2,1-a]isoquinolines | SANDOZ, INC. (US) | 1978-07-11 | — | — | US | disclosed |