⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7024452 | 0.84 | MMP1 (0.53) | — | |
| SCHEMBL16196732 | 0.84 | MMP1 (0.53) | — | |
| SCHEMBL1039374 | 0.82 | — | — | |
| SCHEMBL28045868 | 0.82 | — | — | |
| Water SCHEMBL14563848 | 0.80 | MMP1 (0.50) | — | |
| SCHEMBL28778171 | 0.80 | MMP1 (0.54) | — | |
| SCHEMBL7524679 | 0.80 | MMP1 (0.50) | — | |
| SCHEMBL6990198 | 0.80 | — | — | |
| SCHEMBL2170908 | 0.80 | — | — | |
| SCHEMBL1884481 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693500-A | Carboxamide derivative and agricultural/horticultural plant disease control agent | 组合化学工业株式会社 | 2024-03-12 | — | — | CN | disclosed |
| EP-1772150-A1 | Benzothiophene formulations of a specific dosage | Eli Lilly & Company (US) | 2007-04-11 | — | — | EP | disclosed |
| US-20060106010-A1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY | 2006-05-18 | — | — | US | disclosed |
| US-RE39049-E1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY (US) | 2006-03-28 | — | — | US | disclosed |
| US-RE38968-E1 | Methods for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[b]thien-3-yl-4-[2-(piperidin-1-yl) ethoxyphenylimethanone hydrochloride | ELI LILLY AND COMPANY (US) | 2006-02-07 | — | — | US | disclosed |
| US-6906086-B2 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY (US) | 2005-06-14 | — | — | US | disclosed |
| EP-1438957-A1 | Benzothiophene formulations of a specific dosage | ELI LILLY AND COMPANY (US) | 2004-07-21 | — | — | EP | disclosed |
| US-20030212058-A1 | Methods for inhibiting bone loss | ELI LILLY AND COMPANY | 2003-11-13 | — | — | US | disclosed |
| US-5646137-A | Combination treatment for osteoporosis | ELI LILLY AND COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| EP-0781555-A1 | Benzothiophene formulations of a specific dosage | ELI LILLY AND COMPANY (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0584952-B1 | Improvements in or relating to benzothiophenes | LILLY CO ELI (US) | 1997-05-02 | — | — | EP | disclosed |
| US-5591753-A | BENZOTHIOPHENE DERIVATIVE IN COMBINATION WITH A PROGESTIN | ELI LILLY AND COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5534527-A | TREATMENT OF OSTEOPOROSIS | ELI LILLY AND COMPANY (US) | 1996-07-09 | — | — | US | disclosed |
| US-5457117-A | Method for inhibiting bone loss using 6-hydroxy-2-(4-hydroxyphenyl)-benzo[B][2-(piperidin-1-yl)ethoxyphenylimethanone hydrochloride | ELI LILLY AND COMPANY (US) | 1995-10-10 | — | — | US | disclosed |
| US-5393763-A | Administering benzothiophenes such as raloxifene hydrochloride | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0584952-A1 | Improvements in or relating to benzothiophenes | ELI LILLY AND COMPANY (US) | 1994-03-02 | — | — | EP | disclosed |