SCHEMBL21709276

SCHEMBL21709276

C#CCOC(CN(CC#C)CC#C)c1cc(OC)c(OC)cc1C#C

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
P2RX3 P56373 5/20 0.33
P2RX2 Q9UBL9 5/20 0.33
PYCR1 P32322 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21709252 0.88
SCHEMBL21709143 0.82
SCHEMBL21709248 0.81
SCHEMBL21709270 0.81 P2RX3 (0.38) P2RX3P2RX2
SCHEMBL21709274 0.80 P2RX3 (0.33) P2RX3P2RX2PYCR1
SCHEMBL21709079 0.79
SCHEMBL21709142 0.78
SCHEMBL21709266 0.78 P2RX3 (0.34) P2RX3P2RX2
SCHEMBL21709085 0.78 PPARG (0.38) PYCR1
SCHEMBL21709244 0.71 MAOA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032080-A1 COMPOUND, SALT OF COMPOUND, NEUROMODULATION AGENT, METHOD FOR EVALUATING NEUROMODULATION AGENT, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING SALT OF COMPOUND 学校法人慶應義塾 2020-02-13 WO disclosed