SCHEMBL21709304

SCHEMBL21709304

c1ccc(-c2cc(-c3cc(-c4ccccc4)c4oc5ccccc5c4c3)cc(-c3nc(-c4ccccc4)nc(-c4ccccc4)n3)c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.43
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 3/20 0.43
POLB P06746 2/20 0.43
NPSR1 Q6W5P4 2/20 0.42
KMT2A Q03164 5/20 0.41
TSHR P16473 4/20 0.41
LMNA P02545 4/20 0.41
HTT P42858 1/20 0.41
HPGD P15428 1/20 0.40
HSD17B10 Q99714 3/20 0.40
MAPK1 P28482 2/20 0.40
ALOX5 P09917 2/20 0.39
USP2 O75604 1/20 0.39
AHR P35869 1/20 0.38
MEN1 O00255 4/20 0.38
CSF1R P07333 1/20 0.38
PDGFRB P09619 1/20 0.38
KIT P10721 1/20 0.38
FLT3 P36888 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26047643 0.99 MAPT (0.43) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL25645827 0.96 MAPT (0.44) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL21709139 0.96 MAPT (0.44) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL24526071 0.96 MAPT (0.44) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL24526080 0.96 MAPT (0.44) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL24525890 0.96 MAPT (0.44) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL25645825 0.96 MAPT (0.44) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL24525988 0.96 MAPT (0.46) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL22884337 0.96 MAPT (0.46) MAPTALDH1A1KDM4EPOLBNPSR1
SCHEMBL25646249 0.93 ALOX5 (0.42) MAPTALDH1A1KDM4EPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220199911-A1 AN ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-06-23 US disclosed
WO-2020032424-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING, AS HOST MATERIAL, MIXTURE OF DIFFERENT KINDS OF COMPOUNDS, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2020-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220199911-A1 AN ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT AND AN ELECTRONIC DEVICE THEREOF ESR1, EML4, OCIAD1 MAPT 1551/4885ALDH1A1 1210/4885KDM4E 645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.