SCHEMBL21709354

SCHEMBL21709354

c1ccc2c(c1)ccc1c3cccc(-c4ccc5c(c4)[nH]c4ccccc45)c3sc21

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 8/20 0.43
CYP1A1 P04798 5/20 0.42
CYP1B1 Q16678 5/20 0.42
CYP1A2 P05177 3/20 0.41
AHR P35869 1/20 0.41
ALOX5 P09917 1/20 0.41
ALDH1A1 P00352 1/20 0.38
GPR3 P46089 1/20 0.38
HSD17B10 Q99714 1/20 0.38
BCHE P06276 1/20 0.37
MAPT P10636 1/20 0.36
CDK4 P11802 2/20 0.36
CCND1 P24385 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788285 0.87 AHR (0.44) KIF11AHRALOX5ALDH1A1GPR3
SCHEMBL788246 0.84 ALOX5 (0.46) KIF11AHRALOX5ALDH1A1MAPT
SCHEMBL788802 0.84 HTR2B (0.44) KIF11AHRALOX5ALDH1A1GPR3
SCHEMBL788890 0.84 ALOX5 (0.44) KIF11AHRALOX5ALDH1A1GPR3
SCHEMBL30959738 0.83 ALOX5 (0.59) KIF11AHRALOX5ALDH1A1GPR3
SCHEMBL788292 0.83 ALOX5 (0.59) KIF11AHRALOX5ALDH1A1GPR3
SCHEMBL15893341 0.83 CYP1B1 (0.48) CYP1A1CYP1B1CYP1A2ALOX5ALDH1A1
SCHEMBL30959746 0.82 AHR (0.52) KIF11AHRALDH1A1GPR3HSD17B10
SCHEMBL3273641 0.82 AHR (0.52) KIF11AHRALDH1A1GPR3HSD17B10
SCHEMBL15893344 0.81 CYP1B1 (0.47) CYP1A1CYP1B1CYP1A2AHRALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020032447-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING, AS HOST MATERIAL, MIXTURE OF DIFFERENT KINDS OF COMPOUNDS, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2020-02-13 WO disclosed
WO-2020032424-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING, AS HOST MATERIAL, MIXTURE OF DIFFERENT KINDS OF COMPOUNDS, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2020-02-13 WO disclosed