SCHEMBL21709538

SCHEMBL21709538

Cc1ccc(-c2cc(-c3ccc(C)c(C)c3)cc(-c3ccc(C)c(C)c3)c2)cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 4/20 0.50
TSHR P16473 3/20 0.50
CYP3A4 P08684 2/20 0.50
MCL1 Q07820 1/20 0.48
TP53 P04637 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HTR7 P34969 1/20 0.41
NPC1 O15118 2/20 0.41
NOTUM Q6P988 1/20 0.41
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.41
PTGS2 P35354 2/20 0.38
ALPL P05186 1/20 0.38
CA9 Q16790 1/20 0.38
RAB9A P51151 1/20 0.38
PTGS1 P23219 1/20 0.37
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3084322 0.94 ALDH1A1 (0.55) ALDH1A1TDP1TSHRCYP3A4MCL1
SCHEMBL29702110 0.94 ALDH1A1 (0.55) ALDH1A1TDP1TSHRCYP3A4MCL1
SCHEMBL5390940 0.90 ALDH1A1 (0.52) ALDH1A1TDP1TSHRCYP3A4MCL1
Water SCHEMBL9222873 0.90 ALDH1A1 (0.52) ALDH1A1TDP1TSHRCYP3A4MCL1
Lithium SCHEMBL30110458 0.90 ALDH1A1 (0.60) ALDH1A1TDP1TSHRCYP3A4MCL1
SCHEMBL5396176 0.88 HTR7 (0.52) ALDH1A1TDP1TSHRCYP3A4MCL1
SCHEMBL18987225 0.86 ALDH1A1 (0.46) ALDH1A1TDP1TSHRCYP3A4MCL1
Methoxymethane SCHEMBL29150576 0.85 ALDH1A1 (0.48) ALDH1A1TDP1TSHRCYP3A4MCL1
SCHEMBL1047499 0.82 TDP1 (0.46) ALDH1A1TDP1TSHRCYP3A4MCL1
SCHEMBL28597745 0.82 ALDH1A1 (0.52) ALDH1A1TDP1TSHRCYP3A4MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020219411-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES DUPONT ELECTRONICS, INC. (US) 2020-10-29 WO disclosed
WO-2020033480-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES DUPONT ELECTRONICS, INC. (US) 2020-02-13 WO disclosed
WO-2020033475-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES DUPONT ELECTRONICS, INC. (US) 2020-02-13 WO disclosed