Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PI4KA | P42356 | 3/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722764 | 0.84 | EPHX2 (0.55) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL20247001 | 0.78 | RAB9A (0.61) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL5213085 | 0.76 | EPHX2 (0.60) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL6067867 | 0.75 | EPHX2 (0.59) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL11699532 | 0.74 | PI4KA (0.59) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL13994014 | 0.74 | RAB9A (0.56) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL13996556 | 0.74 | RAB9A (0.59) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL25262011 | 0.73 | KMT2A (0.68) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL30136375 | 0.73 | EPHX2 (0.68) | RAB9AMAPTHTTAXLGFER | |
| SCHEMBL31114573 | 0.73 | KMT2A (0.68) | RAB9AMAPTHTTAXLGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020033782-A1 | ACTIVATORS OF THE RETINOIC ACID INDUCIBLE GENE \"RIG-1\" PATHWAY AND METHODS OF USE THEREOF | Kineta, Inc. (US) | 2020-02-13 | — | — | WO | disclosed |