Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.56 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.56 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24104135 | 1.00 | EPHX2 (0.68) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL558100 | 0.86 | LDHA (0.71) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL5213085 | 0.84 | EPHX2 (0.60) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL28022029 | 0.83 | HSD17B10 (0.60) | EPHX2RAB9ANPC1ALDH1A1HSD17B10 | |
| SCHEMBL9722829 | 0.82 | RAB9A (0.64) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL30136374 | 0.82 | EPHX2 (0.78) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL24104684 | 0.82 | EPHX2 (0.78) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6093737 | 0.82 | CA1 (0.67) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL24104685 | 0.81 | EPHX2 (1.00) | EPHX2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL9722750 | 0.81 | NPC1 (0.76) | EPHX2RAB9ANPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515944-A | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2022-12-23 | — | — | CN | claimed |
| CN-113831301-B | Benzothiazole derivative and application thereof | 沈阳药科大学 | 2023-06-06 | — | — | CN | disclosed |