SCHEMBL217100

SCHEMBL217100

[CH][SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TSHR P16473 5/20 0.33
DAO P14920 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
RAB9A P51151 1/20 0.33
TDP1 Q9NUW8 4/20 0.32
CA2 P00918 3/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
CA4 P22748 2/20 0.32
CA12 O43570 1/20 0.32
GLA P06280 1/20 0.32
CA3 P07451 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
ACHE P22303 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL829629 0.73
SCHEMBL3482296 0.69 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTMAPK1
SCHEMBL38902 0.69 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTMAPK1
Benzene SCHEMBL27873242 0.69 ALDH1A1 (0.40) ALDH1A1TSHRDAONAPRTMAPK1
Cyanide SCHEMBL27342955 0.69 ALDH1A1 (0.33) ALDH1A1TSHRDAONAPRTTDP1
SCHEMBL38651919 0.67 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTMAPK1
SCHEMBL10422510 0.67 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTMAPK1
Ammonia Solution, Strong SCHEMBL3895204 0.67 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTMAPK1
Hydrochloric Acid SCHEMBL1400215 0.67 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTMAPK1
SCHEMBL11588969 0.67 ALDH1A1 (0.38) ALDH1A1TSHRDAONAPRTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP claimed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US claimed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO claimed
US-11492425-B2 Metallocene catalyst compositions and polymerization process therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-11-08 US disclosed
CN-112703210-B Preparation of bimodal rubbers, thermoplastic vulcanizates, and articles made therefrom 埃克森美孚化学专利公司 2022-10-28 CN disclosed
CN-109906234-B Single site catalyst polyolefin polymerization process 埃克森美孚化学专利公司 2022-04-22 CN disclosed
US-20210380734-A1 Metallocene Catalyst Compositions and Polymerization Process Therewith EXXONMOBIL CHEMICAL PATENTS INC. 2021-12-09 US disclosed
US-11078311-B2 Single-site catalyst polyolefin polymerization process EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-08-03 US disclosed
US-11059918-B2 Metallocene catalyst compositions and polymerization process therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-07-13 US disclosed
US-11028196-B2 Polyolefin compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-06-08 US disclosed
EP-3827033-A1 PREPARATION OF BIMODAL RUBBER, THERMOPLASTIC VULCANIZATES, AND ARTICLES MADE THEREFROM ExxonMobil Chemical Patents Inc. (US) 2021-06-02 EP disclosed
US-20090005279-A1 Polyalpha-Olefin Compositions and Processes to Produce the Same EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-01 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11492425-B2 Metallocene catalyst compositions and polymerization process therewith TERT, MDM4, PCBP1 ALDH1A1 1957/4885TSHR 4745/4885DAO 4237/4885
US-20210380734-A1 Metallocene Catalyst Compositions and Polymerization Process Therewith TERT, MDM4, PCBP1 ALDH1A1 1957/4885TSHR 4745/4885DAO 4237/4885
US-11059918-B2 Metallocene catalyst compositions and polymerization process therewith TERT, MDM4, PCBP1 ALDH1A1 1957/4885TSHR 4745/4885DAO 4237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.