SCHEMBL21710697

SCHEMBL21710697

CC(C)c1ccc(-c2ccc3c(c2)c2cc(-c4cccc5c4ccc4c5c5cccc6c7cc(-c8ccccc8-c8ccccc8)ccc7n4c65)cc4c5c6ccccc6ccc5n3c24)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NTSR1 P30989 2/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
CHRNA1 P02708 1/20 0.31
CHRNG P07510 1/20 0.31
CHRNB1 P11230 1/20 0.31
CHRNB2 P17787 1/20 0.31
SLC6A2 P23975 1/20 0.31
CHRNB4 P30926 1/20 0.31
SLC6A4 P31645 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA4 P43681 1/20 0.31
SLC6A3 Q01959 1/20 0.31
CHRND Q07001 1/20 0.31
PPARG P37231 4/20 0.31
PPARA Q07869 4/20 0.31
ALK Q9UM73 1/20 0.30
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21710486 0.96 NTSR1 (0.32) NTSR1CA12CA1CA2CA9
SCHEMBL22679493 0.91 NTSR1 (0.31) NTSR1CHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL22858087 0.87 PIK3CD (0.35) AKR1C3AKR1C2
SCHEMBL22679469 0.85 NTSR1 (0.34) NTSR1ALKGCGRAKR1C3AKR1C2
SCHEMBL22868338 0.85 AKR1B1 (0.34)
SCHEMBL21718104 0.84 KDM4E (0.35) NTSR1CA12CA1CA2CA9
SCHEMBL21717836 0.83 CHRNA1 (0.32) NTSR1CA12CA1CA2CA9
SCHEMBL21710480 0.82 NTSR1 (0.32) NTSR1CA12CA1CA2CA9
SCHEMBL21710478 0.81 PTGES (0.34)
SCHEMBL21718134 0.81 PTGES (0.35) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200052212-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed