Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 13/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.44 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099290 | 0.81 | SRC (0.46) | MAPK10MAPK8 | |
| SCHEMBL30939912 | 0.81 | SRC (0.46) | MAPK10MAPK8 | |
| SCHEMBL21711330 | 0.77 | CCNK (0.39) | CCNKCCNA2CDK2CDK9PSEN1 | |
| SCHEMBL21711356 | 0.76 | MAPK10 (0.45) | MAPK10MAPK8MAPK3CCNKCCNA2 | |
| SCHEMBL21711364 | 0.74 | PTGS1 (0.49) | KDM4E | |
| SCHEMBL21714603 | 0.72 | PSEN1 (0.35) | MAPK10PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21714412 | 0.71 | CLCN2 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL21714567 | 0.68 | PSEN1 (0.39) | MAPK10PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL17071825 | 0.68 | MEN1 (0.49) | MAPK10MAPK3POLBKDM4E | |
| SCHEMBL4484930 | 0.67 | KDM4E (0.36) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195461-B2 | Pyrrolo-dipyridine compounds | OSSIFI THERAPEUTICS LLC (US) | 2025-01-14 | — | — | US | disclosed |
| EP-3836923-B1 | PYRROLO - DIPYRIDINE COMPOUNDS FOR THE TREATMENT OF BONE LOSS | OSSIFI THERAPEUTICS LLC (US) | 2024-10-16 | — | — | EP | disclosed |
| US-20230203036-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2023-06-29 | — | — | US | disclosed |
| US-11655250-B2 | Pyrrolo-dipyridine compounds | OSTEOQC INC. (CA) | 2023-05-23 | — | — | US | disclosed |
| US-20220024922-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2022-01-27 | — | — | US | disclosed |
| EP-3836923-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | Osteoqc Inc. (CA) | 2021-06-23 | — | — | EP | disclosed |
| US-10947236-B2 | Pyrrolo-dipyridine compounds | OSTEOQC INC. (CA) | 2021-03-16 | — | — | US | disclosed |
| WO-2020037004-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSTEOQC INC. (CA) | 2020-02-20 | — | — | WO | disclosed |
| US-20200055853-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203036-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | IMPDH1, DPYD, IGFBP5 | MAPK10 4040/4885MAPK8 4631/4885MAPK3 3752/4885 |
| US-20200055853-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | IMPDH1, DPYD, IGFBP5 | MAPK10 4040/4885MAPK8 4631/4885MAPK3 3752/4885 |
| US-12195461-B2 | Pyrrolo-dipyridine compounds | IMPDH1, DPYD, IGFBP5 | MAPK10 4040/4885MAPK8 4631/4885MAPK3 3752/4885 |
| US-11655250-B2 | Pyrrolo-dipyridine compounds | IMPDH1, DPYD, IGFBP5 | MAPK10 4040/4885MAPK8 4631/4885MAPK3 3752/4885 |
| US-10947236-B2 | Pyrrolo-dipyridine compounds | IMPDH1, DPYD, IGFBP5 | MAPK10 4040/4885MAPK8 4631/4885MAPK3 3752/4885 |
| US-20220024922-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | IMPDH1, DPYD, IGFBP5 | MAPK10 4040/4885MAPK8 4631/4885MAPK3 3752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.