Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CTSC | P53634 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30939912 | 0.75 | SRC (0.46) | CYP1A2CYP3A4 | |
| SCHEMBL21711345 | 0.74 | MAPK10 (0.44) | KDM4E | |
| SCHEMBL29581438 | 0.72 | MAPT (0.47) | PTGS1HTTSMN1; SMN2KDM4ERAB9A | |
| SCHEMBL29760844 | 0.72 | TRPV1 (0.37) | CYP19A1HTTKDM4E | |
| SCHEMBL2035613 | 0.72 | TRPV1 (0.37) | CYP19A1HTTKDM4E | |
| SCHEMBL4484930 | 0.71 | KDM4E (0.36) | KDM4ECYP1A2CYP3A4 | |
| SCHEMBL11900962 | 0.71 | GRM4 (0.35) | HTTKIF11KDM4ECYP1A2 | |
| SCHEMBL1447376 | 0.71 | ALDH1A1 (0.47) | HTTKDM4ECYP1A2 | |
| SCHEMBL21711356 | 0.70 | MAPK10 (0.45) | CTSC | |
| SCHEMBL21711330 | 0.68 | CCNK (0.39) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195461-B2 | Pyrrolo-dipyridine compounds | OSSIFI THERAPEUTICS LLC (US) | 2025-01-14 | — | — | US | disclosed |
| EP-3836923-B1 | PYRROLO - DIPYRIDINE COMPOUNDS FOR THE TREATMENT OF BONE LOSS | OSSIFI THERAPEUTICS LLC (US) | 2024-10-16 | — | — | EP | disclosed |
| US-20230203036-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2023-06-29 | — | — | US | disclosed |
| US-11655250-B2 | Pyrrolo-dipyridine compounds | OSTEOQC INC. (CA) | 2023-05-23 | — | — | US | disclosed |
| US-20220024922-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2022-01-27 | — | — | US | disclosed |
| EP-3836923-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | Osteoqc Inc. (CA) | 2021-06-23 | — | — | EP | disclosed |
| US-10947236-B2 | Pyrrolo-dipyridine compounds | OSTEOQC INC. (CA) | 2021-03-16 | — | — | US | disclosed |
| WO-2020037004-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSTEOQC INC. (CA) | 2020-02-20 | — | — | WO | disclosed |
| US-20200055853-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203036-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | IMPDH1, DPYD, IGFBP5 | PTGS1 316/4885PTGS2 882/4885CYP19A1 718/4885 |
| US-20200055853-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | IMPDH1, DPYD, IGFBP5 | PTGS1 316/4885PTGS2 882/4885CYP19A1 718/4885 |
| US-12195461-B2 | Pyrrolo-dipyridine compounds | IMPDH1, DPYD, IGFBP5 | PTGS1 316/4885PTGS2 882/4885CYP19A1 718/4885 |
| US-11655250-B2 | Pyrrolo-dipyridine compounds | IMPDH1, DPYD, IGFBP5 | PTGS1 316/4885PTGS2 882/4885CYP19A1 718/4885 |
| US-10947236-B2 | Pyrrolo-dipyridine compounds | IMPDH1, DPYD, IGFBP5 | PTGS1 316/4885PTGS2 882/4885CYP19A1 718/4885 |
| US-20220024922-A1 | PYRROLO - DIPYRIDINE COMPOUNDS | IMPDH1, DPYD, IGFBP5 | PTGS1 316/4885PTGS2 882/4885CYP19A1 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.