Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | NCF1 | P14598 | 9/20 | 0.35 |
| ▸ | GRK3 | P35626 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CYBB | P04839 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712417 | 0.85 | MCHR1 (0.39) | MCHR1NCF1GRK3IDO1MAPT | |
| SCHEMBL31050889 | 0.85 | MCHR1 (0.39) | MCHR1NCF1GRK3IDO1MAPT | |
| SCHEMBL21712388 | 0.82 | NPC1 (0.37) | MAPT | |
| SCHEMBL31050887 | 0.82 | NPC1 (0.37) | MAPT | |
| SCHEMBL21730970 | 0.78 | RAF1 (0.46) | RAF1MAP2K1SRC | |
| SCHEMBL21712422 | 0.75 | KCNA5 (0.44) | MAPTRAF1MAP2K1SRC | |
| SCHEMBL31050885 | 0.74 | NPC1 (0.39) | MCHR1NCF1MAPT | |
| SCHEMBL21712407 | 0.74 | NPC1 (0.39) | MCHR1NCF1MAPT | |
| SCHEMBL25958354 | 0.68 | LMNA (0.35) | GRK3IDO1MAPTGSK3BPIM1 | |
| SCHEMBL21712372 | 0.67 | PDE10A (0.33) | MCHR1GRK3IDO1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118515666-A | 2-Amino-quinoline derivatives | 博笛生物科技有限公司 | 2024-08-20 | — | — | CN | disclosed |
| US-11834448-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-12-05 | — | — | US | disclosed |
| US-11834448-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-12-05 | — | — | US | disclosed |
| US-11834448-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2023-12-05 | — | — | US | disclosed |
| EP-3615539-B1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS INC (KY) | 2023-08-09 | — | — | EP | disclosed |
| US-11053240-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2021-07-06 | — | — | US | disclosed |
| US-11053240-B2 | 2-amino-quinoline derivatives | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2021-07-06 | — | — | US | disclosed |
| US-20200055851-A1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2020-02-20 | — | — | US | disclosed |
| US-20200055851-A1 | 2-AMINO-QUINOLINE DERIVATIVES | BIRDIE BIOPHARMACEUTICALS, INC. (KY) | 2020-02-20 | — | — | US | disclosed |
| CN-110637018-A | 2-amino-quinoline derivatives | 博笛生物科技有限公司 | 2019-12-31 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053240-B2 | 2-amino-quinoline derivatives | TLR7, TLR8, TLR1 | MCHR1 1615/4885NCF1 2102/4885GRK3 379/4885 |
| US-20200055851-A1 | 2-AMINO-QUINOLINE DERIVATIVES | TLR7, TLR8, TLR1 | MCHR1 1615/4885NCF1 2102/4885GRK3 379/4885 |
| US-11834448-B2 | 2-amino-quinoline derivatives | TLR7, TLR8, TLR1 | MCHR1 1615/4885NCF1 2102/4885GRK3 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.