Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.55 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.34 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21714647 | 0.80 | DYRK1A (0.59) | DYRK1AHASPINDYRK2BCHEMAOA | |
| SCHEMBL21714577 | 0.77 | DYRK1A (0.65) | DYRK1AHASPINDYRK2BCHEMAOA | |
| SCHEMBL21711313 | 0.76 | DYRK1A (0.54) | DYRK1AHASPINDYRK2BCHEMAOA | |
| SCHEMBL30939885 | 0.71 | DYRK1A (1.00) | DYRK1AHASPINDYRK2BCHEMAOA | |
| SCHEMBL16123489 | 0.71 | DYRK1A (1.00) | DYRK1AHASPINDYRK2BCHEMAOA | |
| SCHEMBL20122801 | 0.69 | DYRK1A (0.58) | DYRK1AHASPINDYRK2CYP19A1BCHE | |
| SCHEMBL30664204 | 0.69 | DYRK1A (0.58) | DYRK1AHASPINDYRK2CYP19A1BCHE | |
| SCHEMBL21711309 | 0.68 | DYRK1A (0.57) | DYRK1AHASPINDYRK2BCHEMAOA | |
| SCHEMBL29423319 | 0.68 | DYRK1A (0.57) | DYRK1AHASPINDYRK2BCHEMAOA | |
| SCHEMBL21711338 | 0.68 | DYRK1A (0.53) | DYRK1AHASPINDYRK2BCHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3837241-B1 | FLUORO SS-CARBOLINE COMPOUNDS FOR THE TREATMENT OF BONE HOMEOSTASIS | OSSIFI THERAPEUTICS LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260097041-A1 | FLUORO BETA-CARBOLINE COMPOUNDS | OSSIFI THERAPEUTICS LLC (US) | 2026-04-09 | — | — | US | disclosed |
| US-12324809-B2 | Fluoro beta-carboline compounds | OSSIFI THERAPEUTICS LLC (US) | 2025-06-10 | — | — | US | disclosed |
| US-20250025472-A1 | FLUORO BETA-CARBOLINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2025-01-23 | — | — | US | disclosed |
| US-11903949-B2 | Fluoro beta-carboline compounds | OSSIFI THERAPEUTICS LLC (US) | 2024-02-20 | — | — | US | disclosed |
| EP-3837241-A1 | FLUORO ß-CARBOLINE COMPOUNDS | Osteoqc Inc. (CA) | 2021-06-23 | — | — | EP | disclosed |
| WO-2020037001-A1 | FLUORO β-CARBOLINE COMPOUNDS | OSTEOQC INC. (CA) | 2020-02-20 | — | — | WO | disclosed |
| US-20200054645-A1 | FLUORO BETA-CARBOLINE COMPOUNDS | OSSIFI THERAPEUTICS LLC | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250025472-A1 | FLUORO BETA-CARBOLINE COMPOUNDS | GLS, AFF1, SLC5A1 | DYRK1A 3077/4885HASPIN 2383/4885DYRK2 2917/4885 |
| US-20260097041-A1 | FLUORO BETA-CARBOLINE COMPOUNDS | CTNNB1, SLC5A1, SLC5A2 | DYRK1A 1466/4885HASPIN 2821/4885DYRK2 888/4885 |
| US-20200054645-A1 | FLUORO BETA-CARBOLINE COMPOUNDS | GLS, AFF1, SLC5A1 | DYRK1A 3077/4885HASPIN 2383/4885DYRK2 2917/4885 |
| US-11903949-B2 | Fluoro beta-carboline compounds | GLS, AFF1, SLC5A1 | DYRK1A 3077/4885HASPIN 2383/4885DYRK2 2917/4885 |
| US-12324809-B2 | Fluoro beta-carboline compounds | GLS, AFF1, SLC5A1 | DYRK1A 3077/4885HASPIN 2383/4885DYRK2 2917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.