SCHEMBL21714647

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21714296	0.80	DYRK1A (0.55)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL21714577	0.77	DYRK1A (0.65)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL16123489	0.74	DYRK1A (1.00)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL29423319	0.74	DYRK1A (0.57)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL30939885	0.74	DYRK1A (1.00)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL21711309	0.74	DYRK1A (0.57)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL21711313	0.71	DYRK1A (0.54)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL21711338	0.70	DYRK1A (0.53)	DYRK1AMAOACCNB2CDK1CCNB1
	SCHEMBL13729807	0.67	TRPA1 (0.37)	MAOAHASPINDYRK2ACHEALDH1A1
	SCHEMBL20122801	0.67	DYRK1A (0.58)	DYRK1AMAOACCNB2CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.