Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | DCK | P27707 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 2/20 | 0.36 |
| ▸ | POLG | P54098 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12473638 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL21714530 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL6369145 | 0.86 | PDE4D (0.56) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL17841790 | 0.86 | PDE4D (0.56) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL23467204 | 0.86 | PDE4D (0.56) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL23227420 | 0.86 | PDE4D (0.56) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL27930788 | 0.86 | PDE4D (0.56) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL28381388 | 0.85 | ALDH1A1 (0.38) | ALDH1A1POLBMEN1USP2KMT2A | |
| SCHEMBL15444797 | 0.85 | POLB (0.42) | ALDH1A1POLBMEN1USP2KMT2A | |
| Hydrochloric Acid SCHEMBL2689516 | 0.85 | PDE4D (0.55) | ALDH1A1POLBMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10751358-B2 | Multitargeted nucleoside derivatives | KALMAN THOMAS I (US) | 2020-08-25 | — | — | US | disclosed |
| US-20200054661-A1 | MULTITARGETED NUCLEOSIDE DERIVATIVES | KALMAN THOMAS I (US) | 2020-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200054661-A1 | MULTITARGETED NUCLEOSIDE DERIVATIVES | PNP, TYMP, UNG | ALDH1A1 1956/4885POLB 36/4885MEN1 3893/4885 |
| US-10751358-B2 | Multitargeted nucleoside derivatives | PNP, TYMP, UNG | ALDH1A1 1956/4885POLB 36/4885MEN1 3893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.