Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | HTR1F | P30939 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21712556 | 0.81 | PARP1 (0.36) | GABRA1GABRB2PLAT | |
| SCHEMBL21715179 | 0.74 | TSHR (0.45) | — | |
| SCHEMBL21714937 | 0.72 | CHRNB2 (0.30) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2918633 | 0.64 | POLB (0.36) | GABRA1GABRB2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL2917663 | 0.62 | CHRNB2 (0.36) | GABRA1GABRB2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL5326 | 0.62 | POLB (0.54) | GABRA1GABRB2CHRNB2CHRNB4CHRNA3 | |
| Hydrochloric Acid SCHEMBL4788809 | 0.60 | POLB (0.52) | GABRA1GABRB2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4179238 | 0.58 | HDAC8 (0.51) | — | |
| SCHEMBL17623531 | 0.57 | CHRNB2 (0.31) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2915344 | 0.57 | PRCP (0.39) | GABRA1GABRB2CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020029980-A1 | SMAD3 INHIBITORS | MOEXA PHARMACEUTICALS LIMITED (CN) | 2020-02-13 | — | — | WO | disclosed |