Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21714966 | 0.72 | GABRA1 (0.32) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL14765393 | 0.60 | — | — | |
| SCHEMBL24258179 | 0.60 | — | — | |
| SCHEMBL15679196 | 0.59 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2915330 | 0.59 | — | — | |
| SCHEMBL7373994 | 0.58 | CHRNB2 (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL17623531 | 0.57 | CHRNB2 (0.31) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL17623526 | 0.57 | MEN1 (0.31) | — | |
| SCHEMBL17623528 | 0.57 | SHMT2 (0.31) | — | |
| SCHEMBL22299786 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020029980-A1 | SMAD3 INHIBITORS | MOEXA PHARMACEUTICALS LIMITED (CN) | 2020-02-13 | — | — | WO | disclosed |