Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | ACP1 | P24666 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21717187 | 0.96 | CHEK2 (0.36) | CHEK2CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL21716352 | 0.93 | CHEK2 (0.35) | CHEK2CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL21717683 | 0.92 | CHEK2 (0.34) | CHEK2CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL21717361 | 0.88 | CHEK2 (0.38) | CHEK2CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL21213076 | 0.86 | CHEK2 (0.41) | CHEK2CYP1A2CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL21717451 | 0.86 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL21716890 | 0.86 | CHEK2 (0.36) | CHEK2ALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL21716792 | 0.84 | MEN1 (0.34) | CHEK2MEN1KMT2A | |
| SCHEMBL21716419 | 0.83 | ROCK2 (0.35) | CYP1A2CYP3A4CYP2D6ALDH1A1ALOX15 | |
| SCHEMBL21717175 | 0.83 | CYP1A2 (0.31) | CYP1A2CYP3A4CYP2D6ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192884-B2 | Heterocyclic compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2021-12-07 | — | — | US | disclosed |
| US-20200048226-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192884-B2 | Heterocyclic compound and organic light-emitting device comprising same | CYP1A1, CYP1B1, CRY1 | CHEK2 2353/4885CYP1A2 6/4885CYP3A4 10/4885 |
| US-20200048226-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CYP1A1, CYP1B1, CRY1 | CHEK2 2353/4885CYP1A2 6/4885CYP3A4 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.