SCHEMBL21716465

SCHEMBL21716465

c1ccc2cc3c(cc2c1)c1ccccc1n3-c1ccc2c3cc4ccccc4cc3n(-c3nc4ccccc4nc3-c3cccc4c3sc3ccccc34)c2c1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
PRKDC P78527 3/20 0.32
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21716814 1.00 ALOX5 (0.33) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL21213455 0.94 ALOX5 (0.37) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL23471823 0.93
SCHEMBL21716976 0.93
SCHEMBL21717012 0.93 ALOX5 (0.30) ALOX5
SCHEMBL21454971 0.90 KDM4E (0.36) ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL24030471 0.89 ALOX5 (0.31) ALOX5PRKDC
SCHEMBL21716273 0.89 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL21717459 0.89 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL23471893 0.88 ALOX5 (0.32) ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11192884-B2 Heterocyclic compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2021-12-07 US disclosed
US-20200048226-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11192884-B2 Heterocyclic compound and organic light-emitting device comprising same CYP1A1, CYP1B1, CRY1 ALOX5 758/4885PRKDC 4408/4885PIK3CD 4021/4885
US-20200048226-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CYP1A1, CYP1B1, CRY1 ALOX5 758/4885PRKDC 4408/4885PIK3CD 4021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.