Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13051520 | 0.89 | GAA (0.40) | RAB9ASMN1; SMN2GAATSHRLMNA | |
| SCHEMBL13055391 | 0.81 | TSHR (0.35) | SMN1; SMN2TSHRTDP1MAPK1 | |
| SCHEMBL3686778 | 0.78 | — | — | |
| SCHEMBL5949707 | 0.77 | EPHX1 (0.48) | RAB9ASMN1; SMN2GAAANPEPRNPEP | |
| SCHEMBL4443941 | 0.76 | — | — | |
| SCHEMBL35664 | 0.75 | — | — | |
| SCHEMBL28396215 | 0.74 | ACHE (0.57) | — | |
| SCHEMBL410374 | 0.74 | ZDHHC20 (0.52) | RAB9ASMN1; SMN2GAAANPEPRNPEP | |
| SCHEMBL12787082 | 0.74 | ANPEP (0.43) | RAB9ASMN1; SMN2GAAANPEPRNPEP | |
| SCHEMBL21577394 | 0.74 | SMN1; SMN2 (0.41) | RAB9ASMN1; SMN2NPC1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022120132-A1 | ANTIBODY-OLIGONUCLEOTIDE COMPLEXES AND USES THEREOF | DYNE THERAPEUTICS, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| US-10668676-B2 | Ophthalmic devices | BAUSCH & LOMB INCORPORATED (US) | 2020-06-02 | — | — | US | disclosed |
| US-20200047437-A1 | OPHTHALMIC DEVICES | MEDICIS PHARMACEUTICAL CORPORATION | 2020-02-13 | — | — | US | disclosed |