SCHEMBL2172133

SCHEMBL2172133

Cc1cc(Cl)cc(C(=O)O)c1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TPMT P51580 3/20 0.70
HCAR1 Q9BXC0 2/20 0.59
CNR2 P34972 1/20 0.47
HCAR2 Q8TDS4 2/20 0.47
TTR P02766 1/20 0.46
RXRA P19793 3/20 0.45
RXRB P28702 3/20 0.45
TSHR P16473 2/20 0.44
ALOX15 P16050 1/20 0.44
ALDH1A1 P00352 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
SRD5A2 P31213 2/20 0.40
KDR P35968 1/20 0.40
NOTUM Q6P988 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29111199 0.98 TPMT (0.67) TPMTHCAR1CNR2HCAR2TTR
SCHEMBL21887694 0.92 TPMT (0.59) TPMTHCAR1CNR2HCAR2TTR
SCHEMBL10830949 0.90 TPMT (0.57) TPMTHCAR1CNR2HCAR2TTR
SCHEMBL31540797 0.84 TPMT (0.54) TPMTHCAR1CNR2TTRRXRA
SCHEMBL40661 0.83 TPMT (0.89) TPMTHCAR1CNR2HCAR2RXRA
SCHEMBL23699 0.83 TPMT (1.00) TPMTHCAR1HCAR2TTRRXRA
SCHEMBL28214359 0.83 TPMT (1.00) TPMTHCAR1HCAR2TTRRXRA
SCHEMBL221684 0.83 TPMT (1.00) TPMTHCAR1CNR2HCAR2RXRA
SCHEMBL69625 0.83 TPMT (0.89) TPMTHCAR1HCAR2TTRRXRA
SCHEMBL668260 0.82 TPMT (0.44) TPMTHCAR1CNR2HCAR2KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-115583895-B Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide 苏州开元民生科技股份有限公司 2023-04-07 CN claimed
CN-115583895-A Synthetic method of 2-amino-5-chloro-N, 3-dimethylbenzamide 苏州开元民生科技股份有限公司 2023-01-10 CN claimed
US-12630533-B2 Heterocyclic compounds useful as KCNT1 inhibitors ACTIO BIOSCIENCES, INC. (US) 2026-05-19 US disclosed
US-20250313548-A1 HETEROCYCLIC COMPOUNDS USEFUL AS KCNT1 INHIBITORS ACTIO BIOSCIENCES, INC. 2025-10-09 US disclosed
WO-2025131957-A1 DIAZINONE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2025-06-26 WO disclosed
CN-118439967-A Preparation method of 2-amino-5-chloro-N, 3-dimethylbenzamide 宁夏贝利特生物科技有限公司 2024-08-06 CN disclosed
WO-2024153106-A1 OXADIAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 中国药科大学 2024-07-25 WO disclosed
CN-115551839-B Heteroaryl-triazole compounds as pesticides 拜耳公司 2024-06-04 CN disclosed
CN-115974807-B 2-Phenyl-5-biphenyl-1, 3, 4-oxadiazole compound, preparation method, pharmaceutical composition and application thereof 中国药科大学 2024-05-31 CN disclosed
CN-115057843-B Preparation method of chlorantraniliprole insecticide 湖南化工研究院有限公司 2024-04-30 CN disclosed
US-5530028-A CONTROLS INSECTS OF THE ORDER LEPIDOPTERA ROHM AND HAAS COMPANY (US) 1996-06-25 US disclosed
EP-0604019-B1 N-Acetonylbenzamides and their use as fungicides ROHM & HAAS (US) 1996-05-08 EP disclosed
US-5344958-A From 3-methoxy-2-(substituted)benzoic acid or ester ROHM AND HAAS COMPANY (US) 1994-09-06 US disclosed
EP-0604019-A1 N-Acetonylbenzamides and their use as fungicides ROHM AND HAAS COMPANY (US) 1994-06-29 EP disclosed
EP-0602794-A2 Insecticidal N'-substituted-N, N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1994-06-22 EP disclosed
US-5254584-A Controlling phytopathogens ROHM AND HAAS COMPANY (US) 1993-10-19 US disclosed
US-4585866-A Treatment of migraine with substituted tropyl benzoate derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1986-04-29 US disclosed
US-4563465-A ANTISEROTONINE AGENTS MERRELL DOW PHARMACEUTICALS INC. (US) 1986-01-07 US disclosed
US-3953595-A Substituted benzoic acid hypolipemic agents PFIZER INC. (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313548-A1 HETEROCYCLIC COMPOUNDS USEFUL AS KCNT1 INHIBITORS KCNT1, KCNT2, KCNN3 TPMT 639/4885HCAR1 1335/4885CNR2 1467/4885
US-12630533-B2 Heterocyclic compounds useful as KCNT1 inhibitors KCNT1, KCNT2, KCNJ2 TPMT 362/4885HCAR1 1501/4885CNR2 338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.