SCHEMBL2172164

SCHEMBL2172164

C=CCNC(=O)NC(CO)(CO)CO

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.42
TSHR P16473 2/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 2/20 0.39
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 4/20 0.35
FAAH O00519 1/20 0.35
RAB9A P51151 1/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 1/20 0.34
HPGD P15428 3/20 0.33
CYP1A2 P05177 1/20 0.33
ATG4B Q9Y4P1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL589028 0.80 SMN1; SMN2 (0.39) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL11404096 0.79 FAAH (0.43) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL5138597 0.77 SMN1; SMN2 (0.52) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL12669780 0.77 SMN1; SMN2 (0.43) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL8060600 0.77 TSHR (0.56) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL252121 0.77 TSHR (0.56) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL17859667 0.75 SMN1; SMN2 (0.50) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL17859666 0.75 SMN1; SMN2 (0.50) SMN1; SMN2TSHRMAPTKMT2ANPSR1
SCHEMBL19512283 0.74 HRH3 (0.35)
SCHEMBL11367872 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2076503-B1 C-PHENYL GLYCITOL COMPOUND FOR THE TREATMENT OF DIABETES TAISHO PHARMACEUTICAL CO LTD (JP) 2013-07-17 EP disclosed
US-7973012-B2 C-phenyl glycitol compound TAISHO PHARMACEUTICAL CO., LTD (JP) 2011-07-05 US disclosed
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND TAISHO PHARMACEUTICAL CO., LTD. (JP) 2010-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100022460-A1 C-PHENYL GLYCITOL COMPOUND SLC5A1, SLC5A2, SLC2A1 SMN1; SMN2 4544/4885TSHR 2437/4885MAPT 1940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.