SCHEMBL217218

SCHEMBL217218

CC=[Hf](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.32
SIGMAR1 Q99720 2/20 0.31
BRD4 O60885 1/20 0.30
CCL2 P13500 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8408407 0.88
SCHEMBL9220721 0.81 SIGMAR1 (0.35) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL1050354 0.80 HTR2A (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL3383168 0.79 HTR2A (0.35) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL1131042 0.79 HTR6 (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL3998079 0.79 SIGMAR1 (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL2778640 0.78
SCHEMBL4323021 0.77 HTR6 (0.38) HTR6HTR2ASIGMAR1KDM4ELMNA
SCHEMBL8702519 0.76 SIGMAR1 (0.32) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL4000061 0.76 SIGMAR1 (0.32) HTR6HTR2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 465 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116023532-A Preparation method of saturated metallocene poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-116023562-A Production process of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-116023534-A Preparation method of poly alpha-olefin 中国石油化工股份有限公司 2023-04-28 CN claimed
CN-116020416-A Method for removing metallocene catalyst 中国石油化工股份有限公司 2023-04-28 CN claimed
US-8969482-B2 Dynamic modulation of metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-03-03 US claimed
EP-2760895-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS Exxon-Mobil Chemical Patents Inc. (US) 2014-08-06 EP claimed
WO-2013048848-A2 DYNAMIC MODULATION OF METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 WO claimed
US-20130085232-A1 Dynamic Modulation of Metallocene Catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-04-04 US claimed
US-8088867-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-01-03 US claimed
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
EP-0294942-B1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL IND (JP) 1994-07-13 EP claimed
EP-0366290-B1 Process for producing olefin polymers CHISSO CORP (JP) 1994-06-29 EP claimed
US-5322902-A Process for the preparation of a polypropylene molding composition HOECHST AKTIENGESELLSCHAFT (DE) 1994-06-21 US claimed
US-5280074-A Process for the preparation of a polypropylene molding composition HOECHST AG (DE) 1994-01-18 US claimed
EP-0422703-B1 CATALYST AND PROCESS FOR THE POLYMERIZATION AND COPOLYMERIZATION OF ALPHA-OLEFINS Enichem Anic S.r.l. (IT) 1993-06-30 EP claimed
EP-0384263-B1 PROCESS FOR PREPARING A STATISTICAL PROPYLENE COPOLYMER HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-11 EP claimed
US-5128295-A Hafnium-titanium-zirconium compound with trialkylaluminum and distannoxane ENICHEM ANIC S.P.A. (IT) 1992-07-07 US claimed
EP-0474391-A2 Polyolefins NIPPON OIL CO. LTD. (JP) 1992-03-11 EP claimed
EP-0422703-A1 Catalyst and process for the polymerization and copolymerization of alpha-olefins Enichem Anic S.r.l. (IT) 1991-04-17 EP claimed
EP-0366290-A2 Process for producing olefin polymers CHISSO CORPORATION (JP) 1990-05-02 EP claimed