Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 8/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30290030 | 1.00 | F12 (0.36) | F12BCHEALDH1A1MEN1GAA | |
| SCHEMBL2172550 | 1.00 | F12 (0.36) | F12BCHEALDH1A1MEN1GAA | |
| SCHEMBL224810 | 1.00 | F12 (0.36) | F12BCHEALDH1A1MEN1GAA | |
| Hydrochloric Acid SCHEMBL27979283 | 0.98 | ALDH1A1 (0.37) | F12BCHEALDH1A1MEN1GAA | |
| Ethane SCHEMBL11061598 | 0.96 | BCHE (0.36) | F12BCHEHTR2C | |
| SCHEMBL1652868 | 0.88 | BCHE (0.34) | F12BCHEALDH1A1MEN1GAA | |
| SCHEMBL793625 | 0.78 | CHRNB4 (0.37) | ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL29636531 | 0.78 | CHRNB4 (0.37) | ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL8703745 | 0.78 | CHRNB4 (0.37) | ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL12350365 | 0.75 | HTR2C (0.39) | F12BCHEALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964925-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-1,2,3,4 -TETRAHYDROQUINOLINES | MITSUBISHI TANABE PHARMA CORP (JP) | 2016-03-30 | — | — | EP | disclosed |
| US-7972836-B2 | Method of enzymatic optical resolution of racemic 4-hydroxy-1,2,3,4-tetrahydroquinoline | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2011-07-05 | — | — | US | disclosed |
| US-20090269821-A1 | Method for Preparing Optically Active 4-Hydroxy-1,2,3,4-Tetrahydroquinoline Compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-10-29 | — | — | US | disclosed |
| EP-1964925-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 4-HYDROXY-1,2,3,4 -TETRAHYDROQUINOLINES | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-09-03 | — | — | EP | disclosed |