Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSV | O60911 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394152 | 0.93 | LMNA (0.57) | LMNAHPGDMCL1MAOBPTGER1 | |
| SCHEMBL30666060 | 0.93 | LMNA (0.57) | LMNAHPGDMCL1MAOBPTGER1 | |
| SCHEMBL6859323 | 0.82 | LMNA (0.54) | LMNAHPGDMCL1MAOBMAPT | |
| SCHEMBL6761438 | 0.82 | PTGER1 (0.56) | LMNAHPGDMCL1PTGER1MAPT | |
| SCHEMBL670626 | 0.81 | TPMT (0.49) | MAPTTDP1 | |
| SCHEMBL7711160 | 0.79 | LMNA (0.56) | LMNAHPGDMAOBMAPTCYP2C19 | |
| SCHEMBL15726040 | 0.78 | PTGER1 (0.57) | LMNAHPGDMCL1MAOBPTGER1 | |
| SCHEMBL5467535 | 0.78 | PTGER1 (0.58) | HPGDMCL1PTGER1MAPTCYP2C9 | |
| SCHEMBL10604980 | 0.77 | LMNA (0.67) | LMNAHPGDMAOBMAPTCYP2C9 | |
| SCHEMBL12379065 | 0.77 | PTGER1 (0.53) | LMNAHPGDMCL1MAOBPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020035058-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATING LIVER DISEASES AND APPLICATION THEREOF | 江苏新元素医药科技有限公司 | 2020-02-20 | — | — | WO | disclosed |