SCHEMBL12379065

SCHEMBL12379065

Cc1cc(C(=O)O)c(C)c(C)c1OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 2/20 0.53
PTPN1 P18031 1/20 0.51
MCL1 Q07820 3/20 0.49
LMNA P02545 1/20 0.48
HPGD P15428 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.47
FOLH1 Q04609 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MAPT P10636 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46
FFAR4 Q5NUL3 1/20 0.45
GLRA1 P23415 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12379069 0.88 GLRA1 (0.52) PTGER1PTPN1MCL1LMNAHPGD
SCHEMBL12379067 0.87 ALDH1A1 (0.51) PTGER1PTPN1LMNAHPGDMEN1
SCHEMBL27678664 0.86 PTGER1 (0.51) PTGER1PTPN1MCL1LMNAHPGD
SCHEMBL28695808 0.85 SLC16A3 (0.43) PTGER1MCL1MEN1KMT2A
SCHEMBL25877912 0.82 PTGER1 (0.48) PTGER1PTPN1MCL1LMNAHPGD
SCHEMBL28322588 0.82 MRGPRX4 (0.48) PTGER1PTPN1MCL1LMNAHPGD
SCHEMBL30666060 0.81 LMNA (0.57) PTGER1PTPN1MCL1LMNAHPGD
SCHEMBL18394152 0.81 LMNA (0.57) PTGER1PTPN1MCL1LMNAHPGD
SCHEMBL9191607 0.81 DHODH (0.49) PTGER1PTPN1MCL1LMNAHPGD
SCHEMBL6761438 0.81 PTGER1 (0.56) PTGER1PTPN1MCL1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7999136-B2 Amide compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-16 US disclosed
US-7956010-B2 Amide compound and use thereof for controlling plant diseases SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-07 US disclosed
US-20100056640-A1 AMIDE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-03-04 US disclosed
US-20100048701-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056640-A1 AMIDE COMPOUND AND USE THEREOF NAT1, AGXT, HAX1 PTGER1 2938/4885PTPN1 2711/4885MCL1 4349/4885
US-20100048701-A1 AMIDE COMPOUND AND USE THEREOF FOR CONTROLLING PLANT DISEASES CYC1, CBR3, CBR1 PTGER1 770/4885PTPN1 1628/4885MCL1 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.