⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2136804 | 0.74 | — | — | |
| SCHEMBL20142052 | 0.70 | — | — | |
| SCHEMBL45145 | 0.60 | — | — | |
| SCHEMBL2877 | 0.59 | — | — | |
| SCHEMBL490224 | 0.59 | — | — | |
| SCHEMBL1923118 | 0.59 | — | — | |
| SCHEMBL23235576 | 0.56 | — | — | |
| SCHEMBL6671938 | 0.56 | — | — | |
| SCHEMBL4663699 | 0.56 | ALDH1A1 (0.36) | — | |
| SCHEMBL40913 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051852-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC BIOLOGICAL INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-03-14 | — | — | WO | claimed |
| CN-116903568-A | Alstoschlarinoid B synthesis method | 西北农林科技大学 | 2023-10-20 | — | — | CN | claimed |
| CN-116478222-A | Process for preparing 3' nucleoside triphosphates and derivatives thereof | 上海兆维科技发展有限公司 | 2023-07-25 | — | — | CN | claimed |
| US-20230076435-A1 | MODIFIER OF FOUR-MEMBERED RING DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) | 2023-03-09 | — | — | US | claimed |
| EP-4053110-A1 | MODIFIER OF FOUR-MEMBERED RING DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-09-07 | — | — | EP | claimed |
| WO-2021083246-A1 | MODIFIER OF FOUR-MEMBERED RING DERIVATIVE, PREPARATION METHOD AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2021-05-06 | — | — | WO | claimed |
| WO-2020228756-A1 | INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-11-19 | — | — | WO | claimed |
| WO-2020156312-A1 | POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2020-08-06 | — | — | WO | claimed |
| CN-114057560-B | Synthetic method of symmetrical spiro-dinaphthyl natural product and analogue thereof | 南开大学 | 2024-04-12 | — | — | CN | disclosed |
| WO-2024051852-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC BIOLOGICAL INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-03-14 | — | — | WO | disclosed |
| CN-116903568-A | Alstoschlarinoid B synthesis method | 西北农林科技大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-116478222-A | Process for preparing 3' nucleoside triphosphates and derivatives thereof | 上海兆维科技发展有限公司 | 2023-07-25 | — | — | CN | disclosed |
| WO-2023126006-A1 | CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF | 厦门赛诺邦格生物科技股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-111410607-B | Process for preparing hexahydrofurofuranol derivative, intermediate and process for preparing the same | 浙江九洲药业股份有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-113056454-A | Quadricyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-20210052723-A1 | NEW SYNTHETIC AGONISTS OF TLR4 RECEPTOR | UNIVERSITA DEGLI STUDI DI MILANO - BICOCCA (IT) | 2021-02-25 | — | — | US | disclosed |
| WO-2020228756-A1 | INHIBITOR CONTAINING BICYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2020-11-19 | — | — | WO | disclosed |
| EP-3707147-A1 | NEW SYNTHETIC AGONISTS OF TLR4 RECEPTOR | Università Degli Studi Di Milano - Bicocca (IT) | 2020-09-16 | — | — | EP | disclosed |
| WO-2020156312-A1 | POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏豪森药业集团有限公司 | 2020-08-06 | — | — | WO | disclosed |
| WO-2020034987-A1 | PRODRUG CONTAINING GLUCURONIDE DERIVATIVE OF JAK INHIBITOR, PREPARATION METHOD THEREFOR, AND USES THEREOF | 江苏豪森药业集团有限公司 | 2020-02-20 | — | — | WO | disclosed |