⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10457542 | 0.71 | LMNA (0.43) | — | |
| SCHEMBL9722374 | 0.71 | LMNA (0.43) | — | |
| SCHEMBL374372 | 0.71 | — | — | |
| SCHEMBL16592168 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL9722398 | 0.71 | LMNA (0.43) | — | |
| SCHEMBL19258 | 0.71 | — | — | |
| SCHEMBL10788720 | 0.71 | — | — | |
| SCHEMBL9722451 | 0.71 | — | — | |
| SCHEMBL822667 | 0.67 | — | — | |
| SCHEMBL7026463 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2694509-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF TROPOMYOSIN-RELATED KINASES | PFIZER LTD (GB) | 2016-05-18 | — | — | EP | claimed |
| CN-101903387-B | 8-anilin0imidaz0pyridines and application thereof as anti-cancer and/or anti-inflammatory agents | GENENTECH INC | 2014-05-21 | — | — | CN | claimed |
| CN-101605794-B | Azabenzofuranyl compounds and methods of use | GENENTECH INC US | 2013-06-12 | — | — | CN | claimed |
| CN-102686587-A | Azaindole glucokinase activators | HOFFMANN LA ROCHE | 2012-09-19 | — | — | CN | claimed |
| CN-101633645-B | N3 alkylated benzimidazole derivatives as mek inhibitors | ARRAY BIOPHARMA INC | 2011-06-22 | — | — | CN | claimed |
| CN-101414662-B | organic electron transport and/or hole blocking material, and synthesis method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2011-01-12 | — | — | CN | claimed |
| CN-101633645-A | N3 alkylated benzimidazole derivatives as mek inhibitors | ARRAY BIOPHARMA INC | 2010-01-27 | — | — | CN | claimed |
| CN-101486682-A | N3 alkylated benzimidazole derivatives as MEK inhibitors | ARRAY BIOPHARMA INC (US) | 2009-07-22 | — | — | CN | claimed |
| CN-101414661-A | Organic electron transport and/or hole blocking material, and synthesis method and application thereof | CHINESE ACAD TECH INST PHYSICS (CN) | 2009-04-22 | — | — | CN | claimed |
| CN-101414662-A | Organic electron transport and/or hole blocking material, and synthesis method and application thereof | CHINESE ACAD TECH INST PHYSICS (CN) | 2009-04-22 | — | — | CN | claimed |
| CN-101124199-A | 5-substituted-2-phenylamino-benzamides as MEK inhibiting substances | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2008-02-13 | — | — | CN | claimed |
| CN-1097051-C | N-heteroaryl-pyridinesulfonamide derivatives and their use as endothelin antagonists | ZENECA LTD (GB) | 2002-12-25 | — | — | CN | claimed |
| JP-6009548-A | — | — | None | — | — | JP | disclosed |
| CN-111269424-A | Polysiloxane compound, preparation method and application thereof | 北京化工大学 | 2020-06-12 | — | — | CN | disclosed |
| CN-106336583-A | Cable insulation material and preparation method thereof | 江苏上上电缆集团有限公司 | 2017-01-18 | — | — | CN | disclosed |
| US-20160151282-A1 | AMPHOTERIC LIPOSOME FORMULATIONS | MARINA BIOTECH INC (US) | 2016-06-02 | — | — | US | disclosed |
| EP-0454042-A2 | Novel platinum complexes | Nippon Kayaku Kabushiki Kaisha (JP) | 1991-10-30 | — | — | EP | disclosed |
| EP-0028351-B1 | REACTIVE DYESTUFFS AND THEIR USE IN DYEING MATERIALS CONTAINING OH OR NH | BAYER AG (DE) | 1984-02-22 | — | — | EP | disclosed |
| EP-0028351-A2 | Reactive dyestuffs and their use in dyeing materials containing OH or NH | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4202873-A | Alkylolamides of iodizable amino acids and immune test reagents containing them | BOEHRINGER MANNHEIM GMBH (DE) | 1980-05-13 | — | — | US | disclosed |