SCHEMBL21723155

SCHEMBL21723155

CCCCCCCCCCC([SiH3])(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
GGPS1 O95749 6/20 0.35
SMPD1 P17405 4/20 0.35
FDPS P14324 9/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CES2 O00748 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4232575 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL29124493 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL6889414 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL27604204 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL21332490 0.90 LMNA (0.30) TSHR
SCHEMBL21541936 0.82 TSHR (0.39) TSHR
SCHEMBL537895 0.79
SCHEMBL23045008 0.79 TSHR (0.36) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL10970539 0.79
SCHEMBL4106511 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113165325-B Polyolefin-based multilayer film with hybrid barrier layer SABIC环球技术有限责任公司 2023-10-03 CN claimed
US-11745477-B2 Polyolefin based multilayer film with a hybrid barrier layer SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-09-05 US claimed
EP-3863850-B1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-06-28 EP claimed
US-20210379874-A1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-09 US claimed
EP-3863850-A1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC Global Technologies B.V. (NL) 2021-08-18 EP claimed
CN-113165325-A Polyolefin-based multilayer film with hybrid barrier layer SABIC环球技术有限责任公司 2021-07-23 CN claimed
EP-3837111-B1 FILM COMPOSITION HAVING ENHANCED OXYGEN BARRIER PROPERTY AND LOW MOISTURE SENSITIVITY SABIC GLOBAL TECHNOLOGIES BV (NL) 2024-12-18 EP disclosed
US-11745477-B2 Polyolefin based multilayer film with a hybrid barrier layer SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-09-05 US disclosed
EP-3863850-B1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-06-28 EP disclosed
US-20210379874-A1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-09 US disclosed
EP-3863850-A1 POLYOLEFIN BASED MULTILAYER FILM WITH A HYBRID BARRIER LAYER SABIC Global Technologies B.V. (NL) 2021-08-18 EP disclosed
CN-113165325-A Polyolefin-based multilayer film with hybrid barrier layer SABIC环球技术有限责任公司 2021-07-23 CN disclosed
EP-3837111-A1 FILM COMPOSITION HAVING ENHANCED OXYGEN BARRIER PROPERTY AND LOW MOISTURE SENSITIVITY SABIC Global Technologies B.V. (NL) 2021-06-23 EP disclosed
WO-2020035449-A1 FILM COMPOSITION HAVING ENHANCED OXYGEN BARRIER PROPERTY AND LOW MOISTURE SENSITIVITY SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-02-20 WO disclosed