SCHEMBL4232575

SCHEMBL4232575

CCCCCCCCCCCCCCCCCCC([SiH3])(OCC)OCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
GGPS1 O95749 6/20 0.35
SMPD1 P17405 4/20 0.35
FDPS P14324 9/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CES2 O00748 1/20 0.33
LPAR1 Q92633 1/20 0.33
LPAR3 Q9UBY5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21723155 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL29124493 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL6889414 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL27604204 1.00 TSHR (0.38) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL21332490 0.90 LMNA (0.30) TSHR
SCHEMBL21541936 0.82 TSHR (0.39) TSHR
SCHEMBL537895 0.79
SCHEMBL23045008 0.79 TSHR (0.36) TSHRTHRBGGPS1SMPD1FDPS
SCHEMBL10970539 0.79
SCHEMBL4106511 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US claimed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US claimed
EP-0945721-A2 Biosensitive element for surface plasmon resonance measurements, and its method of manufacture DAI NIPPON PRINTING CO., LTD. (JP) 1999-09-29 EP claimed
US-20090326097-A1 SURFACE-COATED ALUMINUM OXIDE NANOPARTICLE AND RESIN COMPOSITION THEREOF NISSAN MOTOR CO., LTD. 2009-12-31 US disclosed
EP-2048189-A1 SURFACE-COATED ALUMINUM OXIDE NANOPARTICLE AND RESIN COMPOSITION THEREOF Nissan Motor Co., Ltd. (JP) 2009-04-15 EP disclosed
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US disclosed
US-7087149-B1 Biosensor KATAYANAGI INSTITUTE (JP) 2006-08-08 US disclosed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US disclosed
US-6627397-B1 Comprising thin gold film, plasma polymerization layers, immobilized biologically active substances; use for detection of small amount of target substances in high sensitivity DAI NIPPON PRINTING CO., LTD. (JP) 2003-09-30 US disclosed
EP-1182450-A1 BIOSENSOR Center for Advanced Science and Technology Incubation, Ltd (JP) 2002-02-27 EP disclosed
EP-0945721-A2 Biosensitive element for surface plasmon resonance measurements, and its method of manufacture DAI NIPPON PRINTING CO., LTD. (JP) 1999-09-29 EP disclosed