Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23521965 | 1.00 | ACHE (0.41) | ACHEALDH1A1CYP3A4L3MBTL1SMN1; SMN2 | |
| SCHEMBL21723924 | 1.00 | ACHE (0.41) | ACHEALDH1A1CYP3A4L3MBTL1SMN1; SMN2 | |
| SCHEMBL23521961 | 1.00 | ACHE (0.41) | ACHEALDH1A1CYP3A4L3MBTL1SMN1; SMN2 | |
| SCHEMBL23522182 | 0.84 | NFE2L2 (0.38) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL23522183 | 0.84 | NFE2L2 (0.38) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL23522173 | 0.84 | KMT2A (0.41) | ALDH1A1KMT2AMEN1GAAMAPT | |
| SCHEMBL23522213 | 0.84 | NFE2L2 (0.38) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL23522211 | 0.84 | NFE2L2 (0.38) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL23522180 | 0.84 | NFE2L2 (0.38) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL23522175 | 0.84 | KMT2A (0.41) | ALDH1A1KMT2AMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112839937-B | Isoindolin-1-one derivatives, preparation method and application thereof | 韩国化学研究院 | 2023-08-22 | — | — | CN | disclosed |
| CN-112839937-A | Isoindolin-1-one derivative, method for preparing same, and pharmaceutical composition for preventing or treating cancer comprising same as effective component | 韩国化学研究院 | 2021-05-25 | — | — | CN | disclosed |
| WO-2020036386-A1 | ISOINDOLIN-1-ON DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS EFFECTIVE COMPONENT FOR PREVENTING OR TREATING CANCER | 한국화학연구원 | 2020-02-20 | — | — | WO | disclosed |