SCHEMBL21724100

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21724101	1.00	MAP3K5 (0.45)	MAP3K5MAP4K1RETCDK2ITK
	SCHEMBL21724372	0.89	MAP3K5 (0.48)	MAP3K5MAP4K1RETCDK2ITK
	SCHEMBL29506348	0.88	MAP3K5 (0.56)	MAP3K5MAP4K1RETCDK2ITK
	SCHEMBL15136088	0.88	MAP3K5 (0.56)	MAP3K5MAP4K1RETCDK2ITK
	SCHEMBL23064233	0.85	MAP3K5 (0.45)	MAP3K5RETCDK2ITKMERTK
	SCHEMBL20501037	0.82	MAP3K5 (0.58)	MAP3K5MAP4K1RETCDK2ITK
	SCHEMBL20523134	0.82	MAP3K5 (0.58)	MAP3K5CDK2MAP3K7MAP3K6
	SCHEMBL20523136	0.82	MAP3K5 (0.58)	MAP3K5CDK2MAP3K7MAP3K6
	SCHEMBL21724355	0.82	MAP3K5 (0.52)	MAP3K5RETCDK2ITKMERTK
	SCHEMBL21724058	0.82	MAP3K5 (0.52)	MAP3K5RETCDK2ITKMERTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.