SCHEMBL21724895

SCHEMBL21724895

O=CC(Br)(Br)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6156451 0.72
SCHEMBL6156104 0.72
SCHEMBL9418557 0.69 ALDH1A1 (0.30)
SCHEMBL6155285 0.67
SCHEMBL24190 0.62
SCHEMBL75780 0.62
Benzene SCHEMBL21296191 0.62 KIF11 (0.30)
SCHEMBL22761857 0.62
SCHEMBL808892 0.62
SCHEMBL8396971 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3837245-A1 SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION Innate Tumor Immunity, Inc. (US) 2021-06-23 EP claimed
WO-2020037094-A1 SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION INNATE TUMOR IMMUNITY, INC. (US) 2020-02-20 WO claimed
CN-113861194-B Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof 英维沃化工科技(广州)有限公司 2022-07-05 CN disclosed
CN-113861194-A Pyrrolopyridine-containing bisamide imidazole compound and preparation method and application thereof 英维沃化工科技(广州)有限公司 2021-12-31 CN disclosed
EP-3837245-A1 SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION Innate Tumor Immunity, Inc. (US) 2021-06-23 EP disclosed
WO-2020037094-A1 SUBSTITUED 4-AMINO-1H-IMIDAZO[4,5-C]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION INNATE TUMOR IMMUNITY, INC. (US) 2020-02-20 WO disclosed