Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | TXN | P10599 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732268 | 0.93 | TBXAS1 (0.42) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL21361930 | 0.90 | TBXAS1 (0.41) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL19185674 | 0.89 | TBXAS1 (0.43) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL19185693 | 0.89 | TBXAS1 (0.43) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL19185691 | 0.89 | TBXAS1 (0.43) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL19185636 | 0.89 | TBXAS1 (0.43) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL19185667 | 0.89 | TBXAS1 (0.43) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL19732390 | 0.89 | TBXAS1 (0.43) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| SCHEMBL19185670 | 0.89 | TBXAS1 (0.43) | TBXAS1TERTTXNTXNRD1TAAR1 | |
| Bromide SCHEMBL30124812 | 0.87 | TBXAS1 (0.42) | TBXAS1TERTTXNTXNRD1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766877-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-09-08 | — | — | US | disclosed |
| US-10562884-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10562884-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | TBXAS1 2048/4885TERT 4247/4885TXN 4099/4885 |
| US-10766877-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | TBXAS1 2048/4885TERT 4247/4885TXN 4099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.